Faculty of Physical Education and Health

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Mary Jane De Souza

Mary Jane DeSouza
Associate Professor
Director, Centre for Girls' and Women's Health

Faculty of Physical Education and Health
55 Harbord St.
Toronto, ON M5S 2W6
416-978-6836
maryjane.desouza@utoronto.ca

Degrees
BS, Springfield College MS, Springfield College PhD, University of Connecticut Postdoctoral Fellowship, University of Connecticut Medical School Academic

Websites
"REFUEL" Active Women's Study II
Female Athlete Triad Task Force at U of T

Expertise
Women's health and physical activity Endocrinology of the female athlete
Effects of exercise on the menstrual cycle
Female Athlete Triad (Eating disorders, amenorrhea and osteoporosis)
Luteal Phase Defects and Amenorrhea
Bone Health and Osteoporosis in Female Athletes
Menopause and Osteoporosis

Recent Publications
Loucks, AB, MJ De Souza, NI Williams. Lifetime Exercise and In Vitro Fertilization. Obstetrics and Gynecology. 2007, Feb;109 (2 Pt 1):456-7.

O’Donnell, E., P. Harvey, J. Goodman, De Souza, MJ. Long Term Estrogen Deficiency Lowers Regional Blood Flow, Resting Systolic Blood Pressure and Heart Rate in Exercising Premenopausal Women. American Journal of Physiology: Endocrinology and Metabolism. 2007 Jan 16; [Epub ahead of print].

De Souza, MJ, NI Williams, J Alleyne, JD Vescovi, JL VanHeest, MP Warren. Correction of Misinterpretations and Misrepresentations of the Female Athlete Triad. British Journal of Sports Medicine. 2007 Jan;41(1):58-9.

De Souza, MJ, DK Lee, JL VanHeest, J Scheid, S West, NI Williams. Severity of energy-related menstrual disturbances increases in proportion to indices of energy conservation in exercising women. Fertility and Sterility. 2007, In Press, Accepted December 5, 2006.

De Souza, MJ, S West, S. Jamal, G Hawker and NI Williams. Energy Deficiency and Estrogen Deficiency are associated with Uncoupling of Bone Turnover in Exercising Women. Osteoporosis International. 11/2006, in review.

De Souza, MJ, R Hontscharuk, M Olmsted, T Burke, G Kerr, NI Williams. Drive for Thinness Score is a Proxy Indicator of Energy Deficiency in Exercising Women. Appetite. 2007 May;48(3):359-67. 2006 Dec 20 [Epub ahead of print].

Williams, NI and MJ De Souza. Female Athlete Triad Errors and Misunderstandings. Medicine and Science in Sport and Exercise. Medicine and Science in Sports and Exercise, 2006, 38(5): 3-5.

Thompson, HS, SP Scordilis, and MJ De Souza. Estrogen, progesterone and exercise modulate sarcolemmal permeability in premenopausal women. Hormone Research. 2006;65:151-158.

Kerr, G, E Berman and MJ De Souza. Disordered Eating in Gymnasts: Perspectives of Athletics, Coaches and Parents. Journal of Applied Sports Psychology. 2006, 18(1):28-43.

Berman, E, G Kerr and M.J. De Souza. A Qualitative Exploration of Weight Concerns, Eating and Exercise Behaviors in Recreational Exercisers. Women in Sport and Physical Activity Journal. 14 (1):24-38, 2005.

LE Armstrong, CM Maresh, TA Elliott, N Keith, JL VanHeest, TP Scheett, J Stoppani, DA Judelson, and MJ De Souza. Heat Acclimation and Physical Training Adaptations of Young Women Using Different Contraceptive Hormones. American Journal of Physiology: Endocrinology and Metabolism. 2005, 288(5):E868-75, 2004 Dec 14; [Epub ahead of print].

De Souza, MJ and NI Williams. Beyond Hypoestrogenism in Amenorrheic Athletes: Energy Deficiency as a Contributing Factor for Bone Loss. Current Sports Medicine Reports. 2005, 4(1):38-44.

De Souza, MJ and NI Williams. Physiological Aspects and Clinical Sequelae of Energy Deficiency and Hypoestrogenism in Exercising Women. Human Reproduction Update, 2004, 10(5):433-448.

De Souza, MJ, H McConnell, E O’Donnell, B Lasley, and NI Williams. Fasting Ghrelin Levels in Physically Active Women: Relationship with Menstrual Disturbances and Metabolic Status. Journal of Clinical Endocrinology and Metabolism. 2004, 89(7):3536-3542.

E O’Donnell, and De Souza, MJ. The Cardiovascular Effects of Chronic Hypoestrogenism in Amenorrheic Athletes: A Critical Review. Sports Medicine. 2004, 34(9):601-627.

De Souza, MJ. Menstrual Disturbances in Athletes: A Focus on Luteal Phase Defects. Medicine and Science in Sport and Exercise. 2003, 35(9), 1553-1563.

De Souza, MJ, JP VanHeest, L Demers, and B Lasley. Luteal Phase Deficiency in Recreational Runners: Evidence for a Hypometabolic State. Journal of Clinical Endocrinology and Metabolism. 2003, 88 (1), 337-346.

Klentrou, P, M Cunliffe, J Slack, B Wilk, O Bar-O, MJ De Souza, and M Plyley. Temperature Regulation during Rest and Exercise in the Cold in Premenarcheal and Menarcheal Girls. Journal of Applied Physiology. 2003, 96(4):1393-1398.

Dulipsingh, L, MJ De Souza, Z Ikram, P Fall, A Willard, Z Fang, K Prestwood, L Raisz. The Clinical Utility of Urinary Markers of Bone Turnover in Response to Anti-Resorptive Therapies. The Endocrinologist. 2003, 13(3), 293-299.

Recent Supervised Theses
Sarah West (MSc) “The Role of Cytokines, OPG and RANKL, in Estrogen Deficient Premenopausal Exercising Women” 2004-2006 Jennifer Scheid (MSc) “Gut Peptides in Premenopausal Exercising Women of varying Menstrual Status” 2004-2006

Emma O’Donnell (MSc) “Cardiovascular Indices of Health in Amenorrheic and Eumenorrheic Physically Active Women” 2003-2004

Dan Lee (MSc) “Resting Metabolic Rate and Metabolic Hormones in Amenorrheic and Menstruating Women Indicate a Metabolically-Adjusted Energy Balance” 2004-2005

Rayisa Hontscharuk (MSc) “Understanding the Female Athlete Triad: A Closer Look at the Components of the Female Athlete Triad and their Relationships” 2004-2005